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- W2357703629 abstract "At the time of DREAM trial disclose,the researchers reported their finding that Rosiglitazone could increase bong fracture in women,and although DREAM showed Rosiglitazone could decrease the development of diabetes in high risk prediabetes population,and in ADOPT Rosiglitazone prolonged the durability of glycemic control in five years,Nissen at the Cleveland Clinic reported that rosiglitazone increased the risk of myocardial infarction.Those lead to concerns on the safety of insulin sensitizers.This review will discuss the relationship of development of osteoporosis,arterial calcification and infarction through a proposed hypothesis that arterial calcification although correlates with increased cardiac mortality might be a physiological mechanism of limiting bacterial infection and stability.Rosiglitazone while decreases chronic inflammation and increases repair destabilize the coronary plaque(s) and increases infarction." @default.
- W2357703629 created "2016-06-24" @default.
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- W2357703629 date "2008-01-01" @default.
- W2357703629 modified "2023-09-26" @default.
- W2357703629 title "De-ADOPT the Adaption:Thiazolidinedione drugs,osteoporosis and cardiac infarction" @default.
- W2357703629 hasPublicationYear "2008" @default.
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