FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2357738312> ?p ?o ?g. }

• W2357738312 endingPage "534" @default.
• W2357738312 startingPage "529" @default.
• W2357738312 abstract "To optimize the preparation method of the complex of dihydroartemisinin (DHA) included by hydroxypropyl-beta-cyclodextrin (HP-beta-CD), the molar ratio of DHA and HP-beta-CD, inclusion temperature and inclusion time were optimized by the orthogonal design method with the inclusion drug yield and drug loading as the evaluation indexes. The IR spectrum, DSC and PXRD analyses were employed to characterize the complex and the molecular simulation was processed to investigate the tendency of complex formation. The optimized molar ratio of DHA and HP-beta-CD was 1 : 5, and the optimized preparation was performed under 50 degrees C for 1 h. The IR spectrum, DSC and PXRD analyses indicated the formation of the complex. The low binding free energy and the high solvent accessible surface obtained by molecular simulation showed that DHA could be included by HP-beta-CD and its solubility could be improved significantly. In conclusion, the optimized conditions for the preparation of DHA-HP-beta-CD complex provide a theoretical and experimental basis for further scale-up research." @default.
• W2357738312 created "2016-06-24" @default.
• W2357738312 creator A5021181812 @default.
• W2357738312 creator A5026614129 @default.
• W2357738312 creator A5027024676 @default.
• W2357738312 creator A5031556609 @default.
• W2357738312 creator A5043968617 @default.
• W2357738312 creator A5064323494 @default.
• W2357738312 creator A5077367725 @default.
• W2357738312 date "2012-04-01" @default.
• W2357738312 modified "2023-09-28" @default.
• W2357738312 title "[Preparation and characterization of dihydroartemisinin/ hydroxypropyl-beta-cyclodextrin inclusion complex]." @default.
• W2357738312 cites W1994177952 @default.
• W2357738312 cites W2002101824 @default.
• W2357738312 cites W2022606181 @default.
• W2357738312 cites W2058689045 @default.
• W2357738312 cites W2062790180 @default.
• W2357738312 cites W2095153694 @default.
• W2357738312 cites W2164475968 @default.
• W2357738312 cites W2369683096 @default.
• W2357738312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22799039" @default.
• W2357738312 hasPublicationYear "2012" @default.
• W2357738312 type Work @default.
• W2357738312 sameAs 2357738312 @default.
• W2357738312 citedByCount "0" @default.
• W2357738312 crossrefType "journal-article" @default.
• W2357738312 hasAuthorship W2357738312A5021181812 @default.
• W2357738312 hasAuthorship W2357738312A5026614129 @default.
• W2357738312 hasAuthorship W2357738312A5027024676 @default.
• W2357738312 hasAuthorship W2357738312A5031556609 @default.
• W2357738312 hasAuthorship W2357738312A5043968617 @default.
• W2357738312 hasAuthorship W2357738312A5064323494 @default.
• W2357738312 hasAuthorship W2357738312A5077367725 @default.
• W2357738312 hasConcept C134121241 @default.
• W2357738312 hasConcept C13965031 @default.
• W2357738312 hasConcept C147789679 @default.
• W2357738312 hasConcept C155574463 @default.
• W2357738312 hasConcept C161790260 @default.
• W2357738312 hasConcept C178790620 @default.
• W2357738312 hasConcept C185039092 @default.
• W2357738312 hasConcept C185592680 @default.
• W2357738312 hasConcept C191897082 @default.
• W2357738312 hasConcept C192562407 @default.
• W2357738312 hasConcept C199360897 @default.
• W2357738312 hasConcept C203014093 @default.
• W2357738312 hasConcept C2776120307 @default.
• W2357738312 hasConcept C2776174256 @default.
• W2357738312 hasConcept C2778048844 @default.
• W2357738312 hasConcept C2778371730 @default.
• W2357738312 hasConcept C2778649806 @default.
• W2357738312 hasConcept C2779433975 @default.
• W2357738312 hasConcept C2781160685 @default.
• W2357738312 hasConcept C2910962261 @default.
• W2357738312 hasConcept C2994067411 @default.
• W2357738312 hasConcept C41008148 @default.
• W2357738312 hasConcept C43617362 @default.
• W2357738312 hasConcept C8010536 @default.
• W2357738312 hasConcept C86803240 @default.
• W2357738312 hasConceptScore W2357738312C134121241 @default.
• W2357738312 hasConceptScore W2357738312C13965031 @default.
• W2357738312 hasConceptScore W2357738312C147789679 @default.
• W2357738312 hasConceptScore W2357738312C155574463 @default.
• W2357738312 hasConceptScore W2357738312C161790260 @default.
• W2357738312 hasConceptScore W2357738312C178790620 @default.
• W2357738312 hasConceptScore W2357738312C185039092 @default.
• W2357738312 hasConceptScore W2357738312C185592680 @default.
• W2357738312 hasConceptScore W2357738312C191897082 @default.
• W2357738312 hasConceptScore W2357738312C192562407 @default.
• W2357738312 hasConceptScore W2357738312C199360897 @default.
• W2357738312 hasConceptScore W2357738312C203014093 @default.
• W2357738312 hasConceptScore W2357738312C2776120307 @default.
• W2357738312 hasConceptScore W2357738312C2776174256 @default.
• W2357738312 hasConceptScore W2357738312C2778048844 @default.
• W2357738312 hasConceptScore W2357738312C2778371730 @default.
• W2357738312 hasConceptScore W2357738312C2778649806 @default.
• W2357738312 hasConceptScore W2357738312C2779433975 @default.
• W2357738312 hasConceptScore W2357738312C2781160685 @default.
• W2357738312 hasConceptScore W2357738312C2910962261 @default.
• W2357738312 hasConceptScore W2357738312C2994067411 @default.
• W2357738312 hasConceptScore W2357738312C41008148 @default.
• W2357738312 hasConceptScore W2357738312C43617362 @default.
• W2357738312 hasConceptScore W2357738312C8010536 @default.
• W2357738312 hasConceptScore W2357738312C86803240 @default.
• W2357738312 hasIssue "4" @default.
• W2357738312 hasLocation W23577383121 @default.
• W2357738312 hasOpenAccess W2357738312 @default.
• W2357738312 hasPrimaryLocation W23577383121 @default.
• W2357738312 hasRelatedWork W1966286931 @default.
• W2357738312 hasRelatedWork W2028419342 @default.
• W2357738312 hasRelatedWork W2029140156 @default.
• W2357738312 hasRelatedWork W2034119127 @default.
• W2357738312 hasRelatedWork W2343487946 @default.
• W2357738312 hasRelatedWork W2349071317 @default.
• W2357738312 hasRelatedWork W2352657002 @default.
• W2357738312 hasRelatedWork W2371229227 @default.
• W2357738312 hasRelatedWork W2371278778 @default.
• W2357738312 hasRelatedWork W2376429298 @default.
• W2357738312 hasRelatedWork W2384345877 @default.

• next