Matches in SemOpenAlex for { <https://semopenalex.org/work/W2357763734> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2357763734 endingPage "9" @default.
- W2357763734 startingPage "333" @default.
- W2357763734 abstract "m-Nifedipine(m-Nif 20 mg.kg-1.d-1 ig) was administered orally to male deoxycorticosterone-acetate-salt(DOCA) hypertensive rats for 9 or 12 wk, the affinity and density of dihydropyridines (DHP) binding sites in the membranes of left ventricle (LV) were investigated. Treatment with m-Nif, whether for prevention (6 wk postoperation) or regression (9 wk postoperation) lowered systolic blood pressure, decreased the weight of left ventricle and the Ca2+ concentration in mitochondria in hypertrophied LV. The density (Bmax) and the total number of DHP binding sites in hypertrophied LV were also markedly decreased (450 +/- 25, 462 +/- 36 fmol.mg-1 vs 836 +/- 47 fmol.mg-1 protein, P < 0.001). There was no difference between groups in constant (KD) values of DHP binding sites. These results indicate that m-Nif prevented and regressed cardiac mass in DOCA hypertensive rats through mechanisms that may be associated with their density of DHP binding sites and control of blood pressure." @default.
- W2357763734 created "2016-06-24" @default.
- W2357763734 creator A5054070201 @default.
- W2357763734 creator A5068755596 @default.
- W2357763734 date "1996-01-01" @default.
- W2357763734 modified "2023-09-23" @default.
- W2357763734 title "Effects of m-nifedipine on dihydropyridine binding sites in hypertrophied left ventricular cell membranes from deoxycorticosterone acetate-salt hypertensive rats." @default.
- W2357763734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9275710" @default.
- W2357763734 hasPublicationYear "1996" @default.
- W2357763734 type Work @default.
- W2357763734 sameAs 2357763734 @default.
- W2357763734 citedByCount "0" @default.
- W2357763734 crossrefType "journal-article" @default.
- W2357763734 hasAuthorship W2357763734A5054070201 @default.
- W2357763734 hasAuthorship W2357763734A5068755596 @default.
- W2357763734 hasConcept C126322002 @default.
- W2357763734 hasConcept C134018914 @default.
- W2357763734 hasConcept C185592680 @default.
- W2357763734 hasConcept C2778921608 @default.
- W2357763734 hasConcept C2779066535 @default.
- W2357763734 hasConcept C2781212610 @default.
- W2357763734 hasConcept C2909525131 @default.
- W2357763734 hasConcept C519063684 @default.
- W2357763734 hasConcept C71924100 @default.
- W2357763734 hasConcept C84393581 @default.
- W2357763734 hasConceptScore W2357763734C126322002 @default.
- W2357763734 hasConceptScore W2357763734C134018914 @default.
- W2357763734 hasConceptScore W2357763734C185592680 @default.
- W2357763734 hasConceptScore W2357763734C2778921608 @default.
- W2357763734 hasConceptScore W2357763734C2779066535 @default.
- W2357763734 hasConceptScore W2357763734C2781212610 @default.
- W2357763734 hasConceptScore W2357763734C2909525131 @default.
- W2357763734 hasConceptScore W2357763734C519063684 @default.
- W2357763734 hasConceptScore W2357763734C71924100 @default.
- W2357763734 hasConceptScore W2357763734C84393581 @default.
- W2357763734 hasIssue "5" @default.
- W2357763734 hasLocation W23577637341 @default.
- W2357763734 hasOpenAccess W2357763734 @default.
- W2357763734 hasPrimaryLocation W23577637341 @default.
- W2357763734 hasRelatedWork W1966234050 @default.
- W2357763734 hasRelatedWork W1968526038 @default.
- W2357763734 hasRelatedWork W2059437200 @default.
- W2357763734 hasRelatedWork W2066812352 @default.
- W2357763734 hasRelatedWork W2069936975 @default.
- W2357763734 hasRelatedWork W2075424991 @default.
- W2357763734 hasRelatedWork W2075972388 @default.
- W2357763734 hasRelatedWork W2119799477 @default.
- W2357763734 hasRelatedWork W2171089442 @default.
- W2357763734 hasRelatedWork W2304972347 @default.
- W2357763734 hasVolume "31" @default.
- W2357763734 isParatext "false" @default.
- W2357763734 isRetracted "false" @default.
- W2357763734 magId "2357763734" @default.
- W2357763734 workType "article" @default.