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- W2357852009 abstract "Objective To observe clinical effect of small dosage of Ketamine and Fentanyl or combined with Neostigmine for postoperation analgesia.Methods Totally 40 adult patients who had undergone lower limb operations were randomly divided into two groups according to medication for analgesia.In KF group,Ketamine and Fentanyl were used for analgesia. In KFN group,Ketamine and Fentanyl combined with Neostigmine were employed.Two groups were given full dosage of 2 μg·kg~(-1)Fentanyl through intravenous injection,then analgesia pump(2 ml/h) was used for postopretive analgesia.Medicine in pump were Fentanyl(0.2 μg·kg~(-1)·h~(-1)),Ketamine(120 μg·kg~(-1)·h~(-1)) and Droperidol(2.5 mg),diluted into 100 ml by Natrii chloride.At the same time,the KFN group was injected into subdural space with 1 mg Neostigmine,0.3 mg Hydrobromide and 0.15 mg Bupivacaine,total volume amounted to 10 ml.The analgesic effect and score within 48 h were recorded according to VAS.Results The score within 48 h of KFN group was smaller than that of KF group,but without significant difference(P0.05).There was no significant difference in occurrence of nausea and vomiting(P0.05),and no illusion,urine retention and skin itch occurred in two grorups.Conclusion Small dosage of Ketamine and Fentanyl or combined with subdural injection of Neostigmine can bothe provide satisfactory postoperative analgesic effect." @default.
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- W2357852009 date "2006-01-01" @default.
- W2357852009 modified "2023-09-26" @default.
- W2357852009 title "Intravenous injection of small dosage of ketamine and fentanyl or combined with subdural injection of neostigmine for postoperative analgesia" @default.
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