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- W2357901612 abstract "Objective To explore the curative effect of different doses of intravenous immunoglobin(IVIG) in children with severe hand foot and mouth disease(HFMD) combined with encephalitis. Methods From June to September 2012,75 children with severe HFMD combined with encephalitis were included in the study,and randomly divided into group A(n=25),group B(n=25)and group C(n=25).Besides mannitol,methylprednisolone and other supportive treatments,different doses of IVIG were given in three groups respectively. The curative effect was compared among three groups.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of People′s Hospital of Jimo.Informed consent was obtained from each parents. There was no significant difference in age, disease course and sex among three groups (P0.05). Results There had significant differences in curative effect among three groups(P10.05). There was no significant difference in curative effect between group B and group C(P20.05). Conclusions High-dose IVIG was effective to children with severe HFMD combined with encephalitis,it can relief the symptoms quikly,shorten the course of the disease,avoid the progress of the disease and decrease the incidence rate of complications." @default.
- W2357901612 created "2016-06-24" @default.
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- W2357901612 date "2013-01-01" @default.
- W2357901612 modified "2023-09-24" @default.
- W2357901612 title "Curative Effect Analysis of Different Doses of Intravenous Immunoglobin for Children With Severe Hand Foot and Mouth Disease Combined With Encephalitis" @default.
- W2357901612 hasPublicationYear "2013" @default.
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