Matches in SemOpenAlex for { <https://semopenalex.org/work/W2357936280> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2357936280 abstract "Objective To investigate the effects of dexamethasone on the promoter activities of human α 1(Ⅰ) procollagen gene induced by TGF β 1.Methods Fibroblasts from human skin and hypertrophic scar were primary cultured and subcultured.Cells were transiently transfected with plasmid phCOL2 5,containing -2 5kb of 5flank sequence of human α 1(Ⅰ) procollagen gene,fused to CAT reporter gene by FuGENE Transfection reagent.The effects of dexamethasone and TGF β 1 on the fibroblasts transfected with phCOL2 5 were determined by CAT ELISA.Results Dexamethasone not only reduced the CAT expression of fibroblasts transfected with phCOL2 5 but also inhibited the CAT expression up regulated by TGF β 1 in normal and hypertrophic scar fibroblasts ( P 0 05).Conclusion Dexamethasone can down regulate basal and TGF β 1 induced promoter activities of human α 1(Ⅰ) procollagen gene in normal and hypertrophic scar fibroblasts." @default.
- W2357936280 created "2016-06-24" @default.
- W2357936280 creator A5050440245 @default.
- W2357936280 date "2003-01-01" @default.
- W2357936280 modified "2023-09-23" @default.
- W2357936280 title "Dexamethasone inhibits the promoter activities of human α_1(I) procollagen gene induced by transforming growth factor β_1" @default.
- W2357936280 hasPublicationYear "2003" @default.
- W2357936280 type Work @default.
- W2357936280 sameAs 2357936280 @default.
- W2357936280 citedByCount "0" @default.
- W2357936280 crossrefType "journal-article" @default.
- W2357936280 hasAuthorship W2357936280A5050440245 @default.
- W2357936280 hasConcept C104317684 @default.
- W2357936280 hasConcept C105702510 @default.
- W2357936280 hasConcept C118131993 @default.
- W2357936280 hasConcept C134018914 @default.
- W2357936280 hasConcept C150194340 @default.
- W2357936280 hasConcept C153911025 @default.
- W2357936280 hasConcept C161733203 @default.
- W2357936280 hasConcept C185592680 @default.
- W2357936280 hasConcept C2778698245 @default.
- W2357936280 hasConcept C2780401358 @default.
- W2357936280 hasConcept C54009773 @default.
- W2357936280 hasConcept C55493867 @default.
- W2357936280 hasConcept C64348721 @default.
- W2357936280 hasConcept C86803240 @default.
- W2357936280 hasConceptScore W2357936280C104317684 @default.
- W2357936280 hasConceptScore W2357936280C105702510 @default.
- W2357936280 hasConceptScore W2357936280C118131993 @default.
- W2357936280 hasConceptScore W2357936280C134018914 @default.
- W2357936280 hasConceptScore W2357936280C150194340 @default.
- W2357936280 hasConceptScore W2357936280C153911025 @default.
- W2357936280 hasConceptScore W2357936280C161733203 @default.
- W2357936280 hasConceptScore W2357936280C185592680 @default.
- W2357936280 hasConceptScore W2357936280C2778698245 @default.
- W2357936280 hasConceptScore W2357936280C2780401358 @default.
- W2357936280 hasConceptScore W2357936280C54009773 @default.
- W2357936280 hasConceptScore W2357936280C55493867 @default.
- W2357936280 hasConceptScore W2357936280C64348721 @default.
- W2357936280 hasConceptScore W2357936280C86803240 @default.
- W2357936280 hasLocation W23579362801 @default.
- W2357936280 hasOpenAccess W2357936280 @default.
- W2357936280 hasPrimaryLocation W23579362801 @default.
- W2357936280 hasRelatedWork W1968611376 @default.
- W2357936280 hasRelatedWork W1976127049 @default.
- W2357936280 hasRelatedWork W1980256058 @default.
- W2357936280 hasRelatedWork W1984195841 @default.
- W2357936280 hasRelatedWork W2010045652 @default.
- W2357936280 hasRelatedWork W2029272724 @default.
- W2357936280 hasRelatedWork W2080323238 @default.
- W2357936280 hasRelatedWork W2100778705 @default.
- W2357936280 hasRelatedWork W2365524969 @default.
- W2357936280 hasRelatedWork W2367182317 @default.
- W2357936280 hasRelatedWork W2370714495 @default.
- W2357936280 hasRelatedWork W2372608312 @default.
- W2357936280 hasRelatedWork W2378267919 @default.
- W2357936280 hasRelatedWork W2385299573 @default.
- W2357936280 hasRelatedWork W2398798493 @default.
- W2357936280 hasRelatedWork W2405703177 @default.
- W2357936280 hasRelatedWork W2414940834 @default.
- W2357936280 hasRelatedWork W2419109053 @default.
- W2357936280 hasRelatedWork W3142879090 @default.
- W2357936280 hasRelatedWork W3144254820 @default.
- W2357936280 isParatext "false" @default.
- W2357936280 isRetracted "false" @default.
- W2357936280 magId "2357936280" @default.
- W2357936280 workType "article" @default.