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- W2357964127 abstract "Objective:To establish rabbit fever model.Methods:The model group was injected 0.05μg/kg (A),0.075μg/kg(B),0.1μg/kg(C),0.25μg/kg(D)escherichia coli endotoxin separately into rabbit celebellar cistern,the control group was injected the same quantity of normal saline,measured their body temperature continuously,and observed general state.Results:According to heating process of model group,all had period of rising,period of high fever,and period of decreasing,the process of high fever and decreasing was longer,but the period of rising was shorter,which may be related with the research inject LPS into celebellar cistern directly.The fever process of four model groups met the fever process of human disease. According to heating degree,the fever peak of four model groups were close to mid and high fever margin of human disease.According to general state,which had associated symptoms concern about fever process. Conclusion:Using this method establishing rabbit fever model is stable,feasible and repeatable,the fever reaction of the model group rabbit enhanced with the injection dose of LPS,the different the injection dose of LPS,the different the fever shape.A and B are single peak,C and D are platform peak,you can select the injection dose of LPS under your requirment." @default.
- W2357964127 created "2016-06-24" @default.
- W2357964127 creator A5088434174 @default.
- W2357964127 date "2011-01-01" @default.
- W2357964127 modified "2023-09-25" @default.
- W2357964127 title "Research on Rabbit Fever Model Caused by Endotoxin" @default.
- W2357964127 hasPublicationYear "2011" @default.
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