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- W2357992812 abstract "Objective To evaluate the efficacy and toxicity of XELOX versus OLF in the treatment of advanced gastric cancer.Methods 55 cases with advanced gastric cancer were enrolled into this study.28 patients and 27 patients were randomly divided into XELOX group and OLF grouprespectively.All patients received three cycles of chemotherapy at least.The efficacy and toxicity were evaluated according to WHO standard.Results The overall effective rate and time to disease progression(TTP)in XELOX group were 53.6%(15/28)and 6.0 months,and in OLF group were 48.1%(13/27)and 5.8 months respectively.It was no significant difference between two groups.The incidence of hand-foot syndrome of XELOX was obviously higher than that of OLF(P0.05).The other side-effects such as thrombocytopenia,leukopenia,nausea and vomiting,had no statistical difference between two groups(P0.05).Conclusion Both of the two regimens were effective and well tolerated in treatment of advanced gastric cancer with slight side-effects.But XELOX regimen may be more comfortable to the old patients." @default.
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- W2357992812 date "2009-01-01" @default.
- W2357992812 modified "2023-09-24" @default.
- W2357992812 title "A randomized clinical study of XELOX compared with OLF in the treatment of advanced gastric cancer" @default.
- W2357992812 hasPublicationYear "2009" @default.
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