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- W235800868 abstract "Research Article1 April 1987free access Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets. J.A. Garcia-Sanz J.A. Garcia-Sanz Search for more papers by this author G. Plaetinck G. Plaetinck Search for more papers by this author F. Velotti F. Velotti Search for more papers by this author D. Masson D. Masson Search for more papers by this author J. Tschopp J. Tschopp Search for more papers by this author H.R. MacDonald H.R. MacDonald Search for more papers by this author M. Nabholz M. Nabholz Search for more papers by this author J.A. Garcia-Sanz J.A. Garcia-Sanz Search for more papers by this author G. Plaetinck G. Plaetinck Search for more papers by this author F. Velotti F. Velotti Search for more papers by this author D. Masson D. Masson Search for more papers by this author J. Tschopp J. Tschopp Search for more papers by this author H.R. MacDonald H.R. MacDonald Search for more papers by this author M. Nabholz M. Nabholz Search for more papers by this author Author Information J.A. Garcia-Sanz, G. Plaetinck, F. Velotti, D. Masson, J. Tschopp, H.R. MacDonald and M. Nabholz The EMBO Journal (1987)6:933-938https://doi.org/10.1002/j.1460-2075.1987.tb04841.x PDFDownload PDF of article text and main figures. ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InMendeleyWechatReddit Figures & Info We show that among the subsets of peripheral T lymphocytes (Lyt2+ L3T4- and L3T4+ Lyt2- cells) activated in short-term cultures by stimulation with H-2 incompatible leukocytes 97% of the cytolytic activity and all detectable perforin activity resides in the Lyt2+ cells. But both populations contain approximately equal amounts of a serine protease, granzyme A, the expression of which was previously thought to be restricted to cytolytic T lymphocytes. Previous ArticleNext Article Volume 6Issue 41 April 1987In this issue RelatedDetailsLoading ..." @default.
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- W235800868 title "Perforin is present only in normal activated Lyt2+ T lymphocytes and not in L3T4+ cells, but the serine protease granzyme A is made by both subsets." @default.
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