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- W2358049345 abstract "OBJECTIVE To discuss the effect of Herba leonuri extract on the uterine smooth muscle from isolated mouse uterus. METHODS Extract fat-soluble alkaloid,water soluble alkaloid,flavones and polysaccharide composition from Herba leonuri. By BL-420E+biological signal collection and processing system were recorded in the acetylcholine agonists( M receptor agonists) and atropine( M receptor blockers),isopropyl epinephrine( β receptor agonists),propranolol( β receptor blockers),diphenhydramine( H1 receptor blockers) and nifedipine( Ca2 +channel blockers) after pretreatment,the effect of different extract of Herba leonuri in vitro uterine smooth muscle tension in mice. RESULTS Herba leonuri fat-soluble alkaloid had certain inhibition in vitro uterine contractions which was caused by isopropyl adrenaline,P 0. 05; Herba leonuri water-soluble alkaloids,flavones had certain excitation in vitro uterine relaxation caused by propranolol,diphenhydramine,nifedipine,P 0. 01、0. 05. CONCLUSION Herba leonuri fat-soluble alkaloid inhibition of uterus may be associated with β receptors; Herba leonuri water-soluble alkaloids,flavones excitation of uterus may be related to the H1 receptor,β receptors and Ca2 +-ATPase." @default.
- W2358049345 created "2016-06-24" @default.
- W2358049345 creator A5047992378 @default.
- W2358049345 date "2015-01-01" @default.
- W2358049345 modified "2023-09-25" @default.
- W2358049345 title "The Effect of Herba Leonuri Extract on the Uterine Smooth Muscle from Isolated Mouse Uterus" @default.
- W2358049345 hasPublicationYear "2015" @default.
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