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- W2358078062 abstract "Objective To evaluate the efficacy and safety of aripiprazole in the treatment of adolescent schizophrenia.Methods All 77 patients were randomly assigned to aripiprazole(n=38,the averaged dosage was 22.9 mg/d) or risperidone(n=39,the averaged dosage was 4.3mg/d) treatment for 8 weeks,The efficacy was evaluated with the positive and negative symptom scale(PANSS),The safety were assessed with the treatment emergent symptom scale(TESS),biochemical index,electrocardiogram.Results There was a significant difference between pre and post treatment on PANSS score in the two groups,but every time point between two groups was no significant dissimilarity.Incidence of adverse events in aripiprazole group were lower than the risperidone group,the difference was significant.Conclusion The result show that aripiprazole has similar therapeutic effect to risperidone in treatment of adolescent schizophrenia,and is safe and generally well-tolerated." @default.
- W2358078062 created "2016-06-24" @default.
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- W2358078062 date "2010-01-01" @default.
- W2358078062 modified "2023-09-24" @default.
- W2358078062 title "Research on efficacy and safety of aripiprazole and risperidone in the treatment of adolescent schizophrenia" @default.
- W2358078062 hasPublicationYear "2010" @default.
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