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- W2358097800 abstract "Objective To explore the application of animal anesthesia machine to measuring spikes of external oblique abdominal muscle in rats in order to establish a more objective and effective method for the assessment of the visceral sensitivity in the model of irritable bowel syndrome(IBS).Methods IBS rat models received colorectal irritation in neonates.Responses of external oblique abdominal muscle to colorectal distension in the conscious and slight anesthetic condition were measured to assess the visceral sensitivity in adult rats.Results Either in conscious or slight anesthetic condition,spikes of external oblique abdominal muscle were significantly stronger in IBS rats than those control rats(P0.05).However,there was no significant difference between the two different conditions for both control rats and IBS rats(P0.05).Conclusion Measurement of spikes of external oblique abdominal muscle in slight anesthesia with animal anesthesia machine may be a more effective and objective method to assess visceral sensitivity in IBS rats." @default.
- W2358097800 created "2016-06-24" @default.
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- W2358097800 date "2011-01-01" @default.
- W2358097800 modified "2023-09-23" @default.
- W2358097800 title "Application of Animal Anesthesia Machine to Assessment of Rat Model of Irritable Bowel Syndrome" @default.
- W2358097800 hasPublicationYear "2011" @default.
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