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- W2358103125 abstract "[Objective]To study the detection methods and clinical value of sentinel 1ymph nodes(SLN) biopsy in the breast-conserving surgery for breast cancer. [Method] 65 cases of breast cancer were treated with breast-conserving surgery(BCS) plus adiotherapy,chemotherapy and hormonotherapy postoperatively. 99mTc_DX particles were disected into the breast tissue adjacent to the primary tumor or resection cavity.After 2-4 hours the SLN identified by gamma detector were dissected out,followed by an axillary lymph node dissection(ALND).The SLN and ALN were evaluated with histopathology,immunohistochemistry(1HC) and RT-PCR (examined CKl9 mRNA). [Result] The SLNs were identified in 65 patients,altogether 136 SLNs were harvested,an average of 2.1 SLNs was examined. The sensitivity, accuracy, specificity of SLNB in this study was 96.3%,98.5%,100% respectively.49 cases were received quadrant resection plus axillary lymph node dissection(ALND) 16 cases were received local resection plus ALND.A11 cases were fo11owed up an average of 32.5 months and one case recurred regionally.[Conclusion] Gamma detector probe can be used for SLN detecting in breast cancer patients. SLNB combined with local resection was safe to the breast cancer patients with negative SLN.Breast-conserving surgery plus combined treatments in safe and satisfactory for early breast cancer.It can be considered as the first choice for the treatment of patients with early-stage of breast cancer." @default.
- W2358103125 created "2016-06-24" @default.
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- W2358103125 date "2008-01-01" @default.
- W2358103125 modified "2023-09-25" @default.
- W2358103125 title "Detection and clinical significance of sentinel 1ymph nodes biopsy in breast-conserving surgery for breast cancer" @default.
- W2358103125 hasPublicationYear "2008" @default.
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