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- W2358216870 abstract "Objective To observe the effect of direct-current field stimulation on bcl-2 and bax gene expression in spinal cord motor neurous after operation and to study the mechanism of intervention effect of electric stimulation on apoptosis. Methods In experimental group direct-current stimulators were put into the relevant spinal cord segments and electric stimulation were given instantly after sciatic nerve transection. In control group the same stimulators were put inside without current output. The specimens were taken at 1, 4, 7, 14, 28 days after operation and studied with immunohistochemistry method. The bcl-2 and bax gene expression were observed with light microscope. The spinal cord motor neurons with gene expressed were counted. Results At 4, 7, 14 days after operation in experimental group the number of spinal cord motor neurons with gene bcl-2 expressed was more than that in the control group, while the bax expressed motor neurons were less than those in the control group at 4,7, 14, and 28 days after operation. Conclusions Direct-current field may regulate the expression of the bcl-2 and bax gene after sciatic nerve transection in rats." @default.
- W2358216870 created "2016-06-24" @default.
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- W2358216870 date "2001-01-01" @default.
- W2358216870 modified "2023-09-28" @default.
- W2358216870 title "The impact of direct-current stimulation on apoptotic adjustable gene expression of spinal cord motor neurons after sciatic nerve transection" @default.
- W2358216870 hasPublicationYear "2001" @default.
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