Matches in SemOpenAlex for { <https://semopenalex.org/work/W2358268084> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2358268084 abstract "Objective: To investigate the effects of local injection of HSP47 recombinant plasmid on the skin wound healing process in alloxan-induced diabetic rats and assess the possibility and utility of gene therapy based on HSP47 plasmid. Methods: Diabetic rats with skin wound were randomly distributed into 3 groups. Group A wounds injection normal saline, group B injection pTracer-CMV, group C injection pTracer-CMV-HSP47. Immunohistochemistry, quantitative fluorescent RT-PCR, Western blotting techniques during 3, 6, 9 d after plasmid injection were used to evaluate the expression changes of HSP47 and collagen I. Results: After two consecutive local plasmid injections, the expression of HSP47 and collagen I in pTracer-CMV-HSP47 group was concomitantly strengthened and much intensify than those in A and B group. Conclusion: The expression of HSP47 and collagen I were considerably enhanced after pTracer-CMV-HSP47 local injection, which may help to improve the wound healing in the diabetic rats. The data suggests that HSP47 may possibly become a potential therapeutic target to promote diabetic wound healing in future." @default.
- W2358268084 created "2016-06-24" @default.
- W2358268084 creator A5084804298 @default.
- W2358268084 date "2008-01-01" @default.
- W2358268084 modified "2023-09-23" @default.
- W2358268084 title "Effects of HSP47 Recombinant Plasmid on the Skin Wound Healing Process in the Alloxan-induced Diabetic Rats" @default.
- W2358268084 hasPublicationYear "2008" @default.
- W2358268084 type Work @default.
- W2358268084 sameAs 2358268084 @default.
- W2358268084 citedByCount "0" @default.
- W2358268084 crossrefType "journal-article" @default.
- W2358268084 hasAuthorship W2358268084A5084804298 @default.
- W2358268084 hasConcept C104317684 @default.
- W2358268084 hasConcept C126322002 @default.
- W2358268084 hasConcept C134018914 @default.
- W2358268084 hasConcept C141071460 @default.
- W2358268084 hasConcept C142724271 @default.
- W2358268084 hasConcept C204232928 @default.
- W2358268084 hasConcept C22744801 @default.
- W2358268084 hasConcept C2777397205 @default.
- W2358268084 hasConcept C2780269544 @default.
- W2358268084 hasConcept C2781005915 @default.
- W2358268084 hasConcept C40767141 @default.
- W2358268084 hasConcept C55493867 @default.
- W2358268084 hasConcept C555293320 @default.
- W2358268084 hasConcept C71924100 @default.
- W2358268084 hasConcept C85265743 @default.
- W2358268084 hasConcept C86803240 @default.
- W2358268084 hasConceptScore W2358268084C104317684 @default.
- W2358268084 hasConceptScore W2358268084C126322002 @default.
- W2358268084 hasConceptScore W2358268084C134018914 @default.
- W2358268084 hasConceptScore W2358268084C141071460 @default.
- W2358268084 hasConceptScore W2358268084C142724271 @default.
- W2358268084 hasConceptScore W2358268084C204232928 @default.
- W2358268084 hasConceptScore W2358268084C22744801 @default.
- W2358268084 hasConceptScore W2358268084C2777397205 @default.
- W2358268084 hasConceptScore W2358268084C2780269544 @default.
- W2358268084 hasConceptScore W2358268084C2781005915 @default.
- W2358268084 hasConceptScore W2358268084C40767141 @default.
- W2358268084 hasConceptScore W2358268084C55493867 @default.
- W2358268084 hasConceptScore W2358268084C555293320 @default.
- W2358268084 hasConceptScore W2358268084C71924100 @default.
- W2358268084 hasConceptScore W2358268084C85265743 @default.
- W2358268084 hasConceptScore W2358268084C86803240 @default.
- W2358268084 hasLocation W23582680841 @default.
- W2358268084 hasOpenAccess W2358268084 @default.
- W2358268084 hasPrimaryLocation W23582680841 @default.
- W2358268084 hasRelatedWork W1975389086 @default.
- W2358268084 hasRelatedWork W1981082856 @default.
- W2358268084 hasRelatedWork W1996991205 @default.
- W2358268084 hasRelatedWork W2011330891 @default.
- W2358268084 hasRelatedWork W2016594044 @default.
- W2358268084 hasRelatedWork W2024375705 @default.
- W2358268084 hasRelatedWork W2029710024 @default.
- W2358268084 hasRelatedWork W2079065321 @default.
- W2358268084 hasRelatedWork W2082921332 @default.
- W2358268084 hasRelatedWork W2089608275 @default.
- W2358268084 hasRelatedWork W2098160290 @default.
- W2358268084 hasRelatedWork W2120256241 @default.
- W2358268084 hasRelatedWork W2136217065 @default.
- W2358268084 hasRelatedWork W2169520365 @default.
- W2358268084 hasRelatedWork W2375074942 @default.
- W2358268084 hasRelatedWork W2380406068 @default.
- W2358268084 hasRelatedWork W2386502652 @default.
- W2358268084 hasRelatedWork W2388749607 @default.
- W2358268084 hasRelatedWork W2415461527 @default.
- W2358268084 hasRelatedWork W3143766547 @default.
- W2358268084 isParatext "false" @default.
- W2358268084 isRetracted "false" @default.
- W2358268084 magId "2358268084" @default.
- W2358268084 workType "article" @default.