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- W2358290989 abstract "Objective To analyze the incidence of thrombophlilia in patients with sudden deafness(SD) to help determine the etiology and guide treatment.Methods Forty-three patients(43 ears) with SD as a group and 30 healthy subjects(the control group) were tested.Tests for inherited thrombophilia included anticoagulant Ⅲ(AT-Ⅲ) activity,protein C(PC) activity,protein S(PS) activity,homocysteine(Hcy) and acquired thrombophilia indicator D-dimer(D-D).Results The overall positive rate for inherited thrombophilia in SD group was 46.5%.In particular,the positive rate was 44.1% with Hcy,23.3% with PS and 67.4% with D-D.Compared with the control group,the positive rate was either remarkably increased,as in Hcy and D-D,or decreased as in PS(P 0.05),although AT-Ⅲ and PC showed no significant difference between the two groups(P 0.05).Conclusion The incidence of thrombophilia,especially acquired thrombophilia,is high in SD patients.Both inherited and acquired thrombophilia may contribute to the hypercoagulability in SD patients." @default.
- W2358290989 created "2016-06-24" @default.
- W2358290989 creator A5087601962 @default.
- W2358290989 date "2012-01-01" @default.
- W2358290989 modified "2023-09-23" @default.
- W2358290989 title "Thrombophilia analysis in patients with sudden deafness" @default.
- W2358290989 hasPublicationYear "2012" @default.
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