Matches in SemOpenAlex for { <https://semopenalex.org/work/W2358349743> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2358349743 abstract "To explore the value of tumor maker human serum HER2 extracellular domain(Her2-ECD) combined with CA15-3 and tissue polypeptide specific antigen(TPS) in patients suffered breast cancer,the serum levels of Her2-ECD,TPS and CA15-3 in 45patients with breast cancer,30 women with benign mass and 30 control cases were measured by ELISA.The value of aided diagnosis,curative effect observation and evaluating prognosis were analyzed.The results showed that the serum levels of the three biomarkers in early-stage breast cancer were not significantly different compared with benign and control cases.The TPS were demonstrated significantly higher serum levels in early-stage breast cancer,but the diagnostic sensitivity and specificity(44.00%,33.33%)were too low to meet the demand of early diagnosis.For the advanced and metastasized malignancy,the three serum biomarker levels were significantly higher than that of benign and control cases,and the post-operation levels were lower compared with pre-operation according to the Wilcoxon test results(P0.05.The menopause,tumor size,lymph node metastasis,ER and PR had no effect on the serum levels of the biomarkers.The positive ratios of CA15-3 and Her2-ECD in advanced malignancy were significantly higher than early-stage patients.The serum levels of Her2-ECD were analogous to Her2(IHC) in tissues.Although there were no values for early diagnostic in breast cancer,the serum levels of CA15-3,TPS and Her2-ECD provided worthy information respectively in different aspects.Continuous monitoring conduced to observe the curative effect,disease progression and to evaluate prognosis.As a supplement and extending of Her2 analysis with IHC and FISH,serum Her2-ECD levels could provide independent and impersonal information in the diagnosis and therapy of breast cancer." @default.
- W2358349743 created "2016-06-24" @default.
- W2358349743 creator A5027713071 @default.
- W2358349743 date "2010-01-01" @default.
- W2358349743 modified "2023-09-24" @default.
- W2358349743 title "The Value of Detection of Serum Her2-ECD,CA15-3 and TPS in Patients Suffered Breast Cancer" @default.
- W2358349743 hasPublicationYear "2010" @default.
- W2358349743 type Work @default.
- W2358349743 sameAs 2358349743 @default.
- W2358349743 citedByCount "0" @default.
- W2358349743 crossrefType "journal-article" @default.
- W2358349743 hasAuthorship W2358349743A5027713071 @default.
- W2358349743 hasConcept C118646709 @default.
- W2358349743 hasConcept C121608353 @default.
- W2358349743 hasConcept C126322002 @default.
- W2358349743 hasConcept C142724271 @default.
- W2358349743 hasConcept C143998085 @default.
- W2358349743 hasConcept C146357865 @default.
- W2358349743 hasConcept C151730666 @default.
- W2358349743 hasConcept C185592680 @default.
- W2358349743 hasConcept C2779013556 @default.
- W2358349743 hasConcept C2779399171 @default.
- W2358349743 hasConcept C2781197716 @default.
- W2358349743 hasConcept C2781447364 @default.
- W2358349743 hasConcept C530470458 @default.
- W2358349743 hasConcept C55493867 @default.
- W2358349743 hasConcept C71924100 @default.
- W2358349743 hasConcept C86803240 @default.
- W2358349743 hasConcept C90924648 @default.
- W2358349743 hasConceptScore W2358349743C118646709 @default.
- W2358349743 hasConceptScore W2358349743C121608353 @default.
- W2358349743 hasConceptScore W2358349743C126322002 @default.
- W2358349743 hasConceptScore W2358349743C142724271 @default.
- W2358349743 hasConceptScore W2358349743C143998085 @default.
- W2358349743 hasConceptScore W2358349743C146357865 @default.
- W2358349743 hasConceptScore W2358349743C151730666 @default.
- W2358349743 hasConceptScore W2358349743C185592680 @default.
- W2358349743 hasConceptScore W2358349743C2779013556 @default.
- W2358349743 hasConceptScore W2358349743C2779399171 @default.
- W2358349743 hasConceptScore W2358349743C2781197716 @default.
- W2358349743 hasConceptScore W2358349743C2781447364 @default.
- W2358349743 hasConceptScore W2358349743C530470458 @default.
- W2358349743 hasConceptScore W2358349743C55493867 @default.
- W2358349743 hasConceptScore W2358349743C71924100 @default.
- W2358349743 hasConceptScore W2358349743C86803240 @default.
- W2358349743 hasConceptScore W2358349743C90924648 @default.
- W2358349743 hasLocation W23583497431 @default.
- W2358349743 hasOpenAccess W2358349743 @default.
- W2358349743 hasPrimaryLocation W23583497431 @default.
- W2358349743 hasRelatedWork W1761069005 @default.
- W2358349743 hasRelatedWork W1768281747 @default.
- W2358349743 hasRelatedWork W2078772293 @default.
- W2358349743 hasRelatedWork W2233465251 @default.
- W2358349743 hasRelatedWork W2332591791 @default.
- W2358349743 hasRelatedWork W2348214491 @default.
- W2358349743 hasRelatedWork W2348597086 @default.
- W2358349743 hasRelatedWork W2355201624 @default.
- W2358349743 hasRelatedWork W2356593458 @default.
- W2358349743 hasRelatedWork W2368220717 @default.
- W2358349743 hasRelatedWork W2371842314 @default.
- W2358349743 hasRelatedWork W2374013592 @default.
- W2358349743 hasRelatedWork W2379084409 @default.
- W2358349743 hasRelatedWork W2382708582 @default.
- W2358349743 hasRelatedWork W2382989738 @default.
- W2358349743 hasRelatedWork W2386439061 @default.
- W2358349743 hasRelatedWork W2390785292 @default.
- W2358349743 hasRelatedWork W2400343595 @default.
- W2358349743 hasRelatedWork W3000665428 @default.
- W2358349743 hasRelatedWork W3162068451 @default.
- W2358349743 isParatext "false" @default.
- W2358349743 isRetracted "false" @default.
- W2358349743 magId "2358349743" @default.
- W2358349743 workType "article" @default.