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- W2358378595 abstract "Objective To observe the effect of anti-age herbal prescription-nourishing kidney-essence formula on p53,p21 and p16 expression in D-galactose induced senile rats.Methods Senile rats were induced by D-galactos,and divided into 6 groups :a normal group,a model group,a Tianbaoning group,and 3 nourishing-kidney-essence herb groups(low-dose,middle-dose,and high-dose).Expressions of p53,p21 and p16 in CA1 hippocampus region were quantified by immunohistochemistry.Results Nourishing kidney-essence herbs could inhibit cell cycle related p53,p21 and p16 protein expressions(P0.05).Conclusion Nourishing kidney-essence herbs could inhibit cell cycle related gene p53,p21 and p16 expression,which may be related to the anti-age effect of nourishing kidney-essence herbs." @default.
- W2358378595 created "2016-06-24" @default.
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- W2358378595 date "2009-01-01" @default.
- W2358378595 modified "2023-09-24" @default.
- W2358378595 title "Effect of nourishing kidney-essence herbs on cell cycle related gene expression in D-galactose induced senile rats" @default.
- W2358378595 hasPublicationYear "2009" @default.
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