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- W2358404237 abstract "Objective To study the role of oxidative lung injury in the genesis of oleic acid -induced acute respiratory distress syndrome (ARDS) and the protective effect of vitamin C. Methods Thirty rats were divided into three groups: control, oleic acid, VitC. Oleic acid was injected into the tail vein of rats; VitC was injected into the tail vein before oleic acid injection. Results Two hours after oleic acid injection, it was found in the oleic acid group that the ratio of wet lung-to-body weight and the malondialdehyde (MDA) content in lung were increased(P0.05), the superoxide dismutase (SOD) decreased(P0.05), and the histological disruption was more serious, as compared with those in the other two groups. Conclusion Oxidative lung injury leads to oleic acid-induced ARDS; VitC plays a protective role." @default.
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- W2358404237 date "2004-01-01" @default.
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- W2358404237 title "Protective effect of vitamin C on oleic acid-induced acute respiratory distress syndrome in rats" @default.
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