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- W2358441204 abstract "Most fetuses with aneuploid chromosome like 21 trisomy syndrome can be born alive,but nearly all of them have serious symptoms,such as dementia,which brings heavy burden to the society and the family.Therefore,detection of aneuploidies chromosome is always an essential part of prenatal diagnosis.Classical cytogenetic karyotype analysis is a gold standard for diagnosis of aneuploidies,but the technique has some considerable disadvantages as longer laboratory cycle,intensive labor.With fast development in molecular biology,many new molecular techniques such as PCR,FISH,PRINS,SKY,MALDI/TOFMS and Array CGH have been applied to detect aneuploides.Compared with cytogenetic karyotype analysis,these new approaches are more sensitive and specific with faster and shorter laboratory cycle can be used as a supplement to cytogenetic method." @default.
- W2358441204 created "2016-06-24" @default.
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- W2358441204 date "2007-01-01" @default.
- W2358441204 modified "2023-09-26" @default.
- W2358441204 title "Development in molecular biological methodology of prenatal diagnosis of chromosome aneuploidy" @default.
- W2358441204 hasPublicationYear "2007" @default.
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