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- W2358459826 abstract "Objective:To investigate the effects of the chronic bronchitis treating capsule(CBTC)on cough,phlegm,asthma,and inflammation of chronic bronchitis.Methods:With a rat model of chronic bronchitis induced by lipopolysaccharide(LPS),the effect of CBTC was detected on animals with chronic bronchitis.The relieving cough effect of CBTC was observed on both mice and guinea pigs with coughing caused by aqueous ammonia and citric acid respectively.The eliminating phlegm effect of CBTC was examined using methods of excreting phenol red and glass capillary.The relieving asthma effect of CBTC was determined on guinea pigs with asthma caused by histamine.The anti-inflammation effect of CBTC was finally explored on mice with dimethylbenzene induced ear swelling and cotton ball induced granuloma.Results:CBTC down regulated the increasing number of neutrophilic granulocytes,up regulated the number of alveolar macrophages,and cured the LPS caused chronic bronchitis on rats.CBTC also significantly decreased the times of coughs caused by aqueous ammonia on mice and guinea pigs.CBTC increased the excretion volume of the phenol red in respiratory tracts of mice and the phlegm of rats.CBTC prolonged the incubation period of histamine caused asthma on guinea pigs,which revealed it had anti-asthma function.CBTC inhibited ear swelling and reduced the cotton ball weigh in mice,indicating it had significant anti-inflammation effect. Conclusions:CBTC has significantly curative effect on chronic bronchitis of rats that induced by LPS and simultaneously can eliminating phlegm and anti-inflammation." @default.
- W2358459826 created "2016-06-24" @default.
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- W2358459826 date "2013-01-01" @default.
- W2358459826 modified "2023-09-23" @default.
- W2358459826 title "Experimental Study on the Pharmacological Effects of the Chronic Bronchitis Treating Capsule (CBTC)" @default.
- W2358459826 hasPublicationYear "2013" @default.
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