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- W2358520322 abstract "Platelet aggregability was studied by means of turbidimetry in 60 thromboembolio patients, including myocardial infarction, cerebral thrombosis and diabetes mellitus complicated by vascular disorder, and 40 healthy adults in similar age and sex distribution for comparison. Some factors influencing the sensibility of turbidimetry for the determination, such as the concentration of the aggregation inducing agents, the number of blood platelets, kinetic parameters and discrimination indices were compared and chosen by stepwise regresion analysis with Inteoolor-3621 microcomputer. Kesults showed: (1) Low concentration of the agents gave better distinguishable results. The optimum concentration proposed for each agent was, ADP I μmole, adrenaline 0.5μmole and collagen 25 μg/ml. (2) Four indices were considered to be more sensitive, less variable and less affected by the number of platelets. They are: maximum intensity of aggregation by ADP, the intensity at 3 min after ADP, the intensity at 1 min after adrenaline and maximum intensity by collagen. (3) The most suitable range of the number of blood platelets for the determination was found to be between 2 ×105/mm3 and 2.5 × 105/mm3. (4) It was suggested that a selected set of indices for composite discrimination might be the method of choice for routine determination of platelet hyper aggregability." @default.
- W2358520322 created "2016-06-24" @default.
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- W2358520322 date "1982-01-01" @default.
- W2358520322 modified "2023-09-27" @default.
- W2358520322 title "A STUDY OF CLINICAL APPLICATION OF TURBIDIMETRY FOR THE DETERMINATION OF PLATELET HYPERAGGREGABILITY" @default.
- W2358520322 hasPublicationYear "1982" @default.
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