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- W2358532230 abstract "Objective To investigate the effect of Chenlanhua infusion on ICAM-1 expression in tendon tissue of diabetic foot rats.MethodsDiabetic rat models were established by abdomenal injection of STZ,then fungi were injected into rat digits.Immunohistochemistry method was used to observe the effect of Chenlanhua infusion on expression of ICAM-1 in tendon and muscular tissue.ResultsThe diabetic rat models were set up successfully.The body weight of rats in model groups were significantly decreased,blood glucose and glycosylated hemoglobin increased significantly(P0.05),however,there was no significant difference between the two groups(P0.05).The ICAM-1 expression in tendon tissue in model groups was significantly higher than that of control group(P0.05),which in Chenlanhua group was significantly lower than that of Tangmaikang group(P0.05).ConclusionChenglanhua infusion has no obvious effect of reducing blood glucose,but which could obviously inhibit ICAM-1 expression in tendon tissue,and the inhibition on inflammatory factors may be one of the molecular mechanisms of treating diabetic foot." @default.
- W2358532230 created "2016-06-24" @default.
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- W2358532230 date "2007-01-01" @default.
- W2358532230 modified "2023-09-26" @default.
- W2358532230 title "Effect of Chenlanhua infusion on ICAM-1 expression in tendon tissue of diabetic foot rats" @default.
- W2358532230 hasPublicationYear "2007" @default.
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