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- W2358548220 abstract "Objective To establish a method for the quantitative determination of methylephedrine hydrochloride,guaifenesin and dextromethorphan hydrobromide in compound paracetamol and dextromethorphah syrup. Methods HPLC method was used and the separation was performed on Agilent HC-C18(4.6 mm ×250 mm,5 μm)column with gradient elution using methanol-0.1% phosphoric acid as mobile phase. The flow rate was 1 mL·min-1and the detective wavelength was 216 nm. Results The linear ranges of methylephedrine hydrochloride,guaifenesin and dextromethorphan hydrobromide were 0. 141 2 ~ 1. 412 μg( r = 0. 999 6),0. 605 ~ 6. 05 μg( r =0. 999 8) and 0. 156 8 ~ 1. 568 μg( r = 0. 999 5) respectively. The average recoveries were 100. 05%,98. 69% and 99. 68 % with RSD 2. 24%,1. 85% and 2. 03%,respectively. Conclusions The method is rapid and accurate about determining methylephedrine hydrochloride,guaifenesin and dextromethorphan hydrobromide in compound paracetamol and dextromethorphah syrup." @default.
- W2358548220 created "2016-06-24" @default.
- W2358548220 creator A5083283369 @default.
- W2358548220 date "2014-01-01" @default.
- W2358548220 modified "2023-09-23" @default.
- W2358548220 title "Determination of methylephedrine hydrochloride,guaifenesin,dextromethorphan hydrobromide in compound paracetamol and dextromethorphah syrup by HPLC" @default.
- W2358548220 hasPublicationYear "2014" @default.
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