Matches in SemOpenAlex for { <https://semopenalex.org/work/W2358557602> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2358557602 abstract "Objective To investigate the effects of heroin on plasma uric acid and purine nucleotides catabolism in rat spleen by testing the activities of adenosine deaminase (ADA) and xanthine oxidase (XOD). Methods Rats were administrated with heroin by intraperitoneal injection with increasing dose to develop addiction models. Fifty male Wistar rats were divided into five groups (n=10): control, 3 d adiminigstrationg group, 9 d adiminigstrationg group, 3 d withdrawal group and 8 d withdrawal group. The uric acid concentration in plasma and the activities of ADA and XOD in rat spleen were determined. Results The concentrations of uric acid in plasma in heroin administration groups were significantly increased compared with control group (P0.01). Compared with 9 d administration groups, the concentrations of uric acid in withdrawal groups were not decreased apparently (P0.05). The activities of ADA in spleen in heroin administration groups were significantly increased compared with control group (P0.05).It was decreased apparently in 8 d withdrawal group compared with 9 d administration group. The activity of XOD in spleen in 9 d administration group was increased apparently compared with control group(P0.05), there were no apparently differences between withdrawal groups and 9 d administration group (P0.05), but in the withdrawal groups, the XOD in spleen had taken on a decreased tendence. Conclusion Administration of heroin can enhance the activities of ADA and XOD and promote the purine nucleotides catabolism in spleen." @default.
- W2358557602 created "2016-06-24" @default.
- W2358557602 creator A5086556274 @default.
- W2358557602 date "2005-01-01" @default.
- W2358557602 modified "2023-09-25" @default.
- W2358557602 title "Effects of heroin on adenosine deaminase and xanthine oxidase in spleen and plasma uric acid in rats" @default.
- W2358557602 hasPublicationYear "2005" @default.
- W2358557602 type Work @default.
- W2358557602 sameAs 2358557602 @default.
- W2358557602 citedByCount "0" @default.
- W2358557602 crossrefType "journal-article" @default.
- W2358557602 hasAuthorship W2358557602A5086556274 @default.
- W2358557602 hasConcept C126322002 @default.
- W2358557602 hasConcept C134018914 @default.
- W2358557602 hasConcept C181199279 @default.
- W2358557602 hasConcept C185592680 @default.
- W2358557602 hasConcept C2776991684 @default.
- W2358557602 hasConcept C2778102346 @default.
- W2358557602 hasConcept C2779881121 @default.
- W2358557602 hasConcept C2780159080 @default.
- W2358557602 hasConcept C2780931953 @default.
- W2358557602 hasConcept C2781116151 @default.
- W2358557602 hasConcept C34628245 @default.
- W2358557602 hasConcept C55493867 @default.
- W2358557602 hasConcept C62231903 @default.
- W2358557602 hasConcept C71924100 @default.
- W2358557602 hasConcept C96942376 @default.
- W2358557602 hasConcept C98274493 @default.
- W2358557602 hasConceptScore W2358557602C126322002 @default.
- W2358557602 hasConceptScore W2358557602C134018914 @default.
- W2358557602 hasConceptScore W2358557602C181199279 @default.
- W2358557602 hasConceptScore W2358557602C185592680 @default.
- W2358557602 hasConceptScore W2358557602C2776991684 @default.
- W2358557602 hasConceptScore W2358557602C2778102346 @default.
- W2358557602 hasConceptScore W2358557602C2779881121 @default.
- W2358557602 hasConceptScore W2358557602C2780159080 @default.
- W2358557602 hasConceptScore W2358557602C2780931953 @default.
- W2358557602 hasConceptScore W2358557602C2781116151 @default.
- W2358557602 hasConceptScore W2358557602C34628245 @default.
- W2358557602 hasConceptScore W2358557602C55493867 @default.
- W2358557602 hasConceptScore W2358557602C62231903 @default.
- W2358557602 hasConceptScore W2358557602C71924100 @default.
- W2358557602 hasConceptScore W2358557602C96942376 @default.
- W2358557602 hasConceptScore W2358557602C98274493 @default.
- W2358557602 hasLocation W23585576021 @default.
- W2358557602 hasOpenAccess W2358557602 @default.
- W2358557602 hasPrimaryLocation W23585576021 @default.
- W2358557602 hasRelatedWork W1660294134 @default.
- W2358557602 hasRelatedWork W1991495012 @default.
- W2358557602 hasRelatedWork W1996669090 @default.
- W2358557602 hasRelatedWork W2054840318 @default.
- W2358557602 hasRelatedWork W2055403266 @default.
- W2358557602 hasRelatedWork W2091331617 @default.
- W2358557602 hasRelatedWork W2106911494 @default.
- W2358557602 hasRelatedWork W2321295123 @default.
- W2358557602 hasRelatedWork W2327048873 @default.
- W2358557602 hasRelatedWork W2351387605 @default.
- W2358557602 hasRelatedWork W2359745297 @default.
- W2358557602 hasRelatedWork W2367464485 @default.
- W2358557602 hasRelatedWork W2369671304 @default.
- W2358557602 hasRelatedWork W2388585480 @default.
- W2358557602 hasRelatedWork W2391944414 @default.
- W2358557602 hasRelatedWork W2392945687 @default.
- W2358557602 hasRelatedWork W2810645773 @default.
- W2358557602 hasRelatedWork W2883917465 @default.
- W2358557602 hasRelatedWork W2996535200 @default.
- W2358557602 hasRelatedWork W3116128982 @default.
- W2358557602 isParatext "false" @default.
- W2358557602 isRetracted "false" @default.
- W2358557602 magId "2358557602" @default.
- W2358557602 workType "article" @default.