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- W2358593522 abstract "Objective:To study the expression and significance of survivin for pre-and post-neoadjuvant chemotherapy in cervical squamous cell carcinoma.Methods: Using immunohistochemical method to detect the expression of Survivin for pre-and post-neoadjuvant chemotherapy in 32 cases of cervical squamous cell carcinoma.Results: Positive rates of survivin for all cases pre-and post-chemotherapy group were 68.8%(22/32) and 56.3%(18/32)respectively,(P=0.302),and there were also no significant statistical difference for age goups between 45 years and ≤45 years,phase Ib-IIa and phase IIb-IIIb,high-middle differentiated and poorly differentiated pathological carcinoma.The completed remission rate for neoadjuvant chemotherapy was 100 %(32/32),in which clinical complete remission rate was 40.6%(13/32);and partial remission rate was 59.4%(19/32),in survivin negative group CR rate was 70.0%(7/10),in positive expression group the CR rate was 27.3%(6/22),and there was a significant difference(P=0.023).Conclusion:There is no obvious relation of survivin expression for cervical squamous cell carcinomin with age,clinical stage and the degree of differentiation.There may be closely relation for chemical sensitivity between survivin expression strength for pre-neoadjuvant chemotherapy and a drop of expression for post-chemotherapy,whether survivin is an indicator for cervical squamous cell carcinoma of neoadjuvant chemotherapy sensitivity still could not be verified." @default.
- W2358593522 created "2016-06-24" @default.
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- W2358593522 date "2009-01-01" @default.
- W2358593522 modified "2023-09-24" @default.
- W2358593522 title "Expression and significance of survivin in cervical squamous cell carcinoma for preneoadjuvant chemotherapy and postneoadjuvant chemotherapy" @default.
- W2358593522 hasPublicationYear "2009" @default.
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