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- W2358660147 abstract "[Objective] To investigate the effect of complement C3 and C4 in the recurrent spontaneous abortion(RSA).[Methods] Thirty women who had the history of RSA were involved in study group,in which fifteen of them without pregnancy were in study group I,and other women diagnosed as inevitable abortion were in study group II.Thirty normal women were in control group,according to pregnancy or not,they were divided into control group I and group II.Immunonephelometric assay was used to test complement C3 and C4in the serum of all groups and shortcut immunohistochemistry staining was applied to observe complement C3 and C4 expression in villus tissue of two pregnant groups.[Results] ① The complement C3 and C4 were(1070.4±240.8) mg/L and(244.2±85.8) mg/L in study group serum,and were(929.9±146.6) mg/L and(193.1±65.1) mg/L in the control group(P0.05).② The complement C3 and C4 were(1167.4±142.8) mg/L and(250.9±81.9) mg/L in study group II serum,and were(939.1±120.1) mg/L and(202.8±50.9) mg/L in the control group II(P0.05).③ In villus tissue of study group Ⅱ and control group II,the average points positive intensity of complement C3 were(10.1±4.9) points and(2.2±1.4) points,C4 were(6.6±5.3) points and(1.7±1.0) points(P0.05).[Conclusions] The complement C3 and C4 are increased in patients of RSA.Its activation may be one of immune pathogenesis in RSA." @default.
- W2358660147 created "2016-06-24" @default.
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- W2358660147 date "2011-01-01" @default.
- W2358660147 modified "2023-09-25" @default.
- W2358660147 title "Effect of Complement C_3 and C_4 in the pathogenesis of recurrent spontaneous abortion" @default.
- W2358660147 hasPublicationYear "2011" @default.
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