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- W2358677029 abstract "Objective To study the effect of cilazapril on apoptosis related gene PDCD5(programmed cell death 5) after myocardial infarction in rats.Methods Animal model of myocardial infarction was inflicted by ligating the left anterior descending coronary of rats,24 h later Wistar rats were randomly divided into 2 groups: group A(myocardial infarction group,n=15) and group B(cilazapril group,n=15).At the same time,group C(sham operation group,n=15) was set up.Angiotensin-Ⅱ in the myocardium and the mRNA of PDCD5 were detected after 6 weeks.Results Contracting with group B and group C,the expression of Ang-Ⅱand PDCD5 mRNA in the myocardium in group A was higher(P0.05).The expression of Ang-Ⅱand PDCD5 mRNA in the myocardium in group B was higher(P0.05) than that in group C.Conclusion After myocardial infarction,the expression of Ang-Ⅱand PDCD5 mRNA in the myocardium is increased significantly,which it is higher than that in sham operation group,and which could be reduced with cilazapri." @default.
- W2358677029 created "2016-06-24" @default.
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- W2358677029 date "2006-01-01" @default.
- W2358677029 modified "2023-09-23" @default.
- W2358677029 title "Effect of cilazapril on apoptosis related gene PDCD5 after myocardial infartion in rats" @default.
- W2358677029 hasPublicationYear "2006" @default.
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