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- W2358704410 abstract "Objective To study the serum level changes of neuron specific enolase(NSE),S100β protein and high sensitive C-reactive protein in acute cerebral infarction patients and their clinical significance.Methods The serum level of S100β protein was detected by double antibody sandwich ELISA.Serum high sensitive C-reactive protein and NSE levels were measured by electrochemical process in 33 patients with acute cerebral infarction patients and 25 healthy subjects.We analyzed the relationship between the serum C-reactive protein levels and the severity of disease as well as outcome.The changes of S100β,NSE and CRP were compared with patients with different pathologic conditions and infarction areas.The correlation analysis between S100β,NSE and high sensitive CRP was also made.Results The serum levels of S100β(0.025±0.017)μg/L,NSE(10.957±5.915)μg/L,and high sensitive CRP(7.147±10.503)mg/L in patients with ACI increased significantly as compared with those of control group[(0.017± 0.009)μg/L,(9.972±3.188)μg/L,and(2.679±1.678)mg/L](all P0.05).The serum levels of S100β,NSE and hs-CRP increased with the neurofunction deterioration and infarction area.There was a correlation between the serum levels of S100β,NSE and hs-CRP and severity of acute cerebral infarction.Conclusions Serum S100β protein,NSE and high sensitive C-reactive protein can be used as the indexes in the diagnosis and prognosis of acute cerebral infarction patients,and particularly applicable to patients with stroke who have no access to image checkup.There is the more significance if more factors combine with each other." @default.
- W2358704410 created "2016-06-24" @default.
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- W2358704410 date "2008-01-01" @default.
- W2358704410 modified "2023-09-28" @default.
- W2358704410 title "Correlation Between Serum Levels of S-100B Protein,Neuron Specific Enolase,and High Sensitive C-reactive Protein and Prognosis in Patients with Acute Cerebral Infarction" @default.
- W2358704410 hasPublicationYear "2008" @default.
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