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- W2358792399 abstract "To investigate the significance of HLA-DR and HLA-ABC antigen expression in ovarian epithelial carcinoma and to provide the theoretic al basis on tumor immune therapy targeting HLA.Streptomyces avidin-peroxidase(S-P)immunohistochemical method was used to detect the HLA-DR a nd HLA-ABC antigen expression in normal ovarian tissues,benign and ovarian carcinomas.①The positive rate of HLA-DR in ovaria n carcinomas was obviously higher than those in benig n ovarian tumor and normal ovarian tissues,which was obviously higher in stageⅠthan that in stageⅢⅣ;The positive rate of HLA-DR was obviously higher in high differentiated group than those in m edian and low differentiated groups.②The positive rate of HLA-ABC in ovarian carcinomas was ob viously lower than those in benign ovarian tumor and normal ovarian tissues,which was obviously higher in stageⅠthan that in stageⅢⅣ.③The positive rate of HLA-DRHLA-ABC were positively c orrelated with the survival rate of o varian carcinoma.[Conclusion]The abnormal expression of HLA-DR H LA-ABC may be associated with the pathogenesis of ovarian carcinoma.HLA-DR HLA-ABC may be the prognostic factors of ovarian epithelial carcinoma." @default.
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- W2358792399 date "2004-01-01" @default.
- W2358792399 modified "2023-09-28" @default.
- W2358792399 title "Clinical Significance of Expression of HLA-DR and HLA-ABC Antigens in Epithelial Ovarian Carcinoma" @default.
- W2358792399 hasPublicationYear "2004" @default.
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