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- W2358797650 abstract "ObjectiveTo systematically evaluate the effectiveness and safety of Puerarin on diabetic peripheral neuropathy. MethodsA systematic review and evaluation of all available relevant randomized or quasi-randomized controlled trials of Puerarin for diabetic peripheral neuropathy from Cochrane Controlled Trials Register (150 issue of 2003), Medline (1966-2003. 2), EMbase (1984-2001. 12. 4), and the Chinese Biological Medicine Database (1978-2003. 2) were performed. The selection of studies, data extraction, and assessment of methodological quality were performed independently by two reviewers. The following outcomes were assessed: effectiveness of clinical symptoms, sensory nerve and motor nerve conduction velocities, and severe adverse events of Puerarin. ResultsTen randomized controlled clinical trials including 726 patients met the inclusion criteria. At the end of the treatment, compared to general treatment or vitamin B, Puerarin showed significant positive effects on the total effect rate of therapy and increased peripheral nerve conduction velocity. No severe adverse events were observed during the treatment period. However, most included trials show some degree of study design or analysis defect. ConclusionsOur analysis suggests that Puerarin appears to be an effective and safe treatment for diabetic peripheral neuropathy. However, due to the low quality trials included in this review, more rigorously designed, randomized, double-blind, placebo-controlled trials of Puerarin for diabetic peripheral neuropathy are needed to further assess its usefulness in diabetes peripheral neuropathy patients." @default.
- W2358797650 created "2016-06-24" @default.
- W2358797650 creator A5043992437 @default.
- W2358797650 date "2004-01-01" @default.
- W2358797650 modified "2023-09-26" @default.
- W2358797650 title "Puerarin in the Treatment of Diabetic Peripheral Neuropathy: A Systematic Review" @default.
- W2358797650 hasPublicationYear "2004" @default.
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