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- W2358825035 abstract "Objective:To observe the changes of serum IL-6 levels in the rat model of insulin resistance(IR)(induced) by highfat-sugar diet,and investigate the relationship between IL-6 and IR.Methods: Thirty male SD rats were randomly divided into 3 groups.Group N(n=10) was given basic diet.Group HH(n=10) was given highfat-sugar diet.Group HL(n=10) was given high-fat-sugar diet for 4 weeks,and then bred with basic diet for 6 weeks.The body weight,serum glucose,insulin and serum IL-6 were measured every week.(Results:)After 3 weeks,the IR index of Group HH and Group HL were increased significantly(P0.01),and it didn't develop in Group N.After 7 weeks,both Group HH and Group HL had IR,but its IR tendency in Group HL was obviously slower than that in Group HH(P0.01).The plasma IL-6 in three groups all increased after 3 weeks(P 0.05),but no significant difference was observed between them(P 0.05).The plasma IL-6 level was positively correlated with body weight.Conclusion: IL-6 is not correlated with IR induced by high fat and sugar diet,and may be associated with the body weight of rats in growth and development period." @default.
- W2358825035 created "2016-06-24" @default.
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- W2358825035 date "2006-01-01" @default.
- W2358825035 modified "2023-09-23" @default.
- W2358825035 title "Experimental study on the relationship between IL-6 and insulin resistance" @default.
- W2358825035 hasPublicationYear "2006" @default.
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