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- W2358825338 abstract "Objective: To investigate the expression of MRP2 protein and its correlation with the chemoresistance in esophageal squamous cell carcinoma.Methods: 70 cases with esophageal squamous cell carcinomas were chosen.The expression of MRP2 in esophageal squamous cell carcinomas and pericarcinoma tissues was detected with immunohistochemical Elivision TM plus non-hiotin technique.The chemoresistace was assayed by MTT method.Results: The positive expression rates of MRP2 protein in esophageal squa-mous cell carcinomas and pericarcinoma tissues were 58.6 % and 5.0 % respectively.The positive expression rates of MRP2 protein in esophageal squamous cell carcinomas were significantly higher than that in pericarcinoma tissues(P0.01).The expression of MRP2 was negatively correlated to the chemoresistance,except mitomycin and paclitaxel.Conclusion: The MRP2 protein is overexpressed and the chemoresistance of the chemotherapeutics probably correlates with the MRP2 expression in esophageal squamous cell carcinomas." @default.
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- W2358825338 date "2012-01-01" @default.
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- W2358825338 title "The expression of MRP2 protein and its correlation with the chemoresistance in esophageal squamous cell carcinoma." @default.
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