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- W2358865050 abstract "Objective To review the predictive values of brachial-ankle pulse wave velocity(baPWV) in the diagnosis of coronary heart disease(CHD) and correlation between the changes of baPWV(baPWV%) and severity of coronary stenosis(SYNTAX integral).Methods The patients having coronary angiography(CAG,n=452) were divided into the CHD group(n=251) and non-CHD group(n=201) according to the outcomes of CAG.The CHD group was divided again into three sub-groups:mild group,moderate group and severe group according to the severity of coronary stenosis(SYNTAX grading).The changes of baPWV and baPWV% were detected by using the measure system of PWV in all patients before CAG.CHD was diagnosed based on the outcomes of CAG.The predictive value of baPWV% was reviewed by using receive operating characteristic curve(ROC) and the correlation between baPWV% and SYNTAX integral was analyzed in the CHD group.Results The differences of baPWV and baPWV% were statistically significant between the CHD group and non-CHD group(P0.01).In three sub-groups,the difference of baPWV% was statistically significant among mild group,moderate group and severe group(P0.01).The cutpoint was 22.5% in ROC of baPWV% to SYNTAX and the area under the curve was the largest.The specificity for predicting CHD was 75.2% and sensitivity was 60.6%.There was a moderate and positive correlation between baPWV% and SYNTAX integral(rho=0.545,P0.001).Conclusion The predictive values of baPWV and baPWV% are moderate in the diagnosis of CHD and the specificity and sensitivity are limited." @default.
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- W2358865050 date "2011-01-01" @default.
- W2358865050 modified "2023-09-24" @default.
- W2358865050 title "Predictive value of pulse wave velocity in diagnosis of coronary heart disease and severity of coronary stenosis" @default.
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