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- W2358962017 abstract "Objective To evaluate the effect of Qi-zhong granules on the intervention of IL-2 and IFN-r level in rat sera with the drug and its action on influenza virus A,and to investigate its mechanism of Qizhong granules.Methods Thirty six rats were randomly devided into six groups: three groups treated with Qi-zhong granules respectively with low,middle and high doses,a controlgroup with herbal medicine Yu-ping feng granules,a control group with virazole and a blank group.Rat sera with the drug were detected IL-2 and IFN-r levels by double antibody ABC-ELISA.The method of preventive administration was adopted.The cytopathic effect of MDCK cells(CPE) was observed to calculate the inhibition ratio of CPE caused by influenza cells.Results Compared with the blank group,both IL-2 and IFN-r levels were boosted in drug treated groups(P 0.05 or P 0.01).IL-2 levels were higher in groups with low lose of Qi-zhong granula、Yu-ping feng granules treated group and virazole treated group.There was no significant differences above three groups(P 0.05).The highest level of IFN-r appeared in the high lose of Qi-zhong granules treated group,There are significant differences as compared with the group treated by Yu-ping feng granules and virazole(P 0.05)respectively.In a test of anti influenza virus,the administration groups were of no remarkable effect on inhibiting virus.Conclusion Qi-zhong granules can boost levels of IL-2 and IFN-r in rats,thus enhancing body's immune function.However,Qi-zhong granules have no significant effect in inhibiting influenza A virus.It is indicated that Qi-zhong granules may have effect on prevention of influenza by regulating body's immunity or interfering immunopathogenesis of virus." @default.
- W2358962017 created "2016-06-24" @default.
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- W2358962017 date "2007-01-01" @default.
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- W2358962017 title "Experimental observation of Qi-zhong granules in preventing influenza" @default.
- W2358962017 hasPublicationYear "2007" @default.
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