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- W2358974615 abstract "Objective To detect DNA adduct in lung cancer tissues and analyze the factors influencing formation of DNA adduct. Methods DNA was extracted from the tumor tissues derived from 34 patients with lung cancer. DNA adducts were analyzed using 32P-postlabeling method with P 1 nuclear modification. Results DNA adduct level was significantly higher in smoking patients than that in non smoking patients(P < 0.05). DNA adduct level was related to the histological classification, degree of cell differentiation and lymph node metastasis, but not to age and sex. Conclusion DNA adduct level might be used as a potential marker to estimate malignant degree for lung cancer.DOI: 10.3779/j.issn.1009-3419.2003.03.05" @default.
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- W2358974615 date "2003-06-20" @default.
- W2358974615 modified "2023-09-23" @default.
- W2358974615 title "Level of DNA adduct in lung cancer tissues and its influencing factors" @default.
- W2358974615 doi "https://doi.org/10.3779/j.issn.1009-3419.2003.03.05" @default.
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