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- W2358989852 abstract "Cell-penetrating peptides(CPP) are small peptides that are able to ferry much larger molecules into cells independent of classical endocytosis. Through the recent study of natural existing CPP, the generally mechanism by which this internalization takes place has been described partly. CPP are basic amino acid-riched polypeptides, a part of this domain can be folded in an α-helix structure with amphipathic characteristics. PEP-1 and MPG which were designed on the basis of these properties can constitute a powerful tool for the delivery of active protein or other biomacromolecules both in cultured cells and in vivo, without requiring any covalent coupling, which provide a more efficient strategy for gene therapy." @default.
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- W2358989852 date "2006-01-01" @default.
- W2358989852 modified "2023-09-26" @default.
- W2358989852 title "Advances in Cell-Penetrating Peptides" @default.
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