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- W2359001511 abstract "Objective: To study effect on immunological function of Isatis indigotica polysaccharide(IIP) in mice.Methods: To establish an immunosuppressive mouse model by intraperitoneal injecting cyclophosphamide.Those mice were given the different doses of IIP through supplementation.The T-lymphocyte subsets were measured with staphylococcal protein A rosette test.The serum contents of IgM,IgG and IgA were determined with immunoturbidimetry.The serum content of soluble interleukin-2 receptor(sIL-2R) was determined with enzyme-linked immunosorbent assay.Detect the thymus index.The spleen lymphocyte proliferation and delayed type hypersensitivity were measured by MTT.Results: IIP significantly increased the percentages of CD3+andCD4+ T-lymphocytes subsets,decreased the content of sIL-2R in mice.IIP also significantly increased the production of IgM,IgG and IgA,promoted spleen lymphocyte proliferation and delayed type hypersensitivity.Conclusion: IIP modulates the immunity in immunosuppressive model mice." @default.
- W2359001511 created "2016-06-24" @default.
- W2359001511 creator A5074501677 @default.
- W2359001511 date "2012-01-01" @default.
- W2359001511 modified "2023-09-23" @default.
- W2359001511 title "Effect on Immunological Function of Isatis Indigotica Polysaccharide in Mice" @default.
- W2359001511 hasPublicationYear "2012" @default.
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