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- W2359005752 abstract "Objective To study mucosa micro-structure pattern of early cardia cancer and precancerous lesions and its diagnostic value by using enhanced magnification endoscope.Methods One hundred and thirty-six cases of patients from high incidence area were examined by magnifying endoscope with staining of 1.5% acetic acid.The mucosa patterns were classified into five types as follows:type A(round spot pit),type B(short stick pit or thin linear pit),type C(villus pattern),type D(furrow or cerebroid pattern) and type E(irregular pattern and abnormal tumor vessel formed).Subsequently,the correlation between mucosal patterns and histopathology diagnosis was analysed by using statistic methods.Results In the study,483 lesions(including inflammation,precancerous lesions and early cardia cancer) were observed with enhanced magnification endoscope.The mucosal patterns of type A and B were mainly found from inflammation mucosa.Type A typifies fundic glands epithelium,and type B typifies cardiac glands epithelium.Their constituent ratios were 100%(150/150) and 87.7%(143/163) respectively.Type C was mainly found from intestinal metaplasis(IM).The ratio of type C was significantly higher than that of type B or type D(P0.01).Type D was mainly found from low-grade intraepithelial neoplasty(IN).The ratio of type D(55.9%) was significantly higher than that of type C and type E(P0.01).The ratio(41.7%) of type E was significantly higher than type C and type D in high-grade IN(P0.01).The mucosal pattern of 21 cases early cardia cancer all represented type E.There were positive correlations between the five mucosal patterns and the disease degree of cardia(Spearman correlation=0.850,P0.01).Conclusion The distribution of five mucosal pits is correlated with histopathology diagnosis of cardia lesions.Type C,D,E represent the distinctive manifestations of IM,low-grade IN,and early cardia cancer respectively.It is helpful to early detect cardia cancer and precancerous lesions in high incidence area through observing mucosal patterns with enhanced magnification endoscope." @default.
- W2359005752 created "2016-06-24" @default.
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- W2359005752 date "2008-01-01" @default.
- W2359005752 modified "2023-09-23" @default.
- W2359005752 title "Value of mucosal micro-structure pattern in visualization diagnosis of early cardia cancer and precancerous lesions" @default.
- W2359005752 hasPublicationYear "2008" @default.
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