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- W2359010228 abstract "OBJECTIVE To observe the influence of the complex prescription metformin and berberine(CPMB)on metabolism disorder of lipid of the diabetic rats.METHODS To administered the CPMB(metformin:berberine=60∶130)to Diabetic rats established by injection of streptozotocin(STZ)for 3 months.the changes of the triglyceride(TG)and cholesterol were tested.RESULTS After the administration of CPMB,high dose 400mg·kg-1,middle dose 200 mg·kg-1and low dose 100 mg·kg-1,respectively,the metabolism disorder of lipid were remarkable ameliorated.TG in each dose group was decreased significantly(P0.01).Total cholesterol(CHO)in high dose treatment groups was decreased significantly(P0.01).Low-density lipoprotein(LDL)in high and middle dose groups was decreased significantly(P0.01).High-density lipoprotein(HDL-C)in high and middle dose groups was increased significantly(P0.01).CONCLUSION The CPMB can ameliorate the metabolism disorder of lipid of the diabetic rats and have advantage of the treatment of the diabetic complications." @default.
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- W2359010228 date "2007-01-01" @default.
- W2359010228 modified "2023-09-25" @default.
- W2359010228 title "Effect of the comples prescription metformin and derberine on the disturbance of lipid metabolism of the Diabetic Rats" @default.
- W2359010228 hasPublicationYear "2007" @default.
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