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- W2359014722 abstract "The paper is to make a general review over the research advances with one of the most representative nanomaterial fullerene (C_(60)), which is regarded as a kind of up-to-date nanomaterial with a wide range of applications due to excellent physical and chemical properties. Excellent in use as it is, it has been found that fullerene and its water-soluble derivatives can react to organisms and bring about toxicity to human beings, which has caused enormous concern of scientists and the governmental departments concerned. As is known, fullerene water suspensions and water-soluble fullerene derivatives can be prepared by chemical modification, stabilization of surfactants, solvent exchange and long-term stirring methods. In this way, it can be said that fullerene is likely to be exposed to human bodies via air, water and soil in the environment and in its vivo behavior. Therefore, the paper takes as its central focus the review of the status-quo of the eco-toxicity of fullerene itself and its water-soluble derivatives. As a matter of fact, the current research reports show that fullerene and its water-soluble derivatives are toxic in different levels to the cells, bacteria, invertebrates and fishes. Generation of C_(60)-mediated reactive oxygen species (ROS) can contribute a great deal to the toxicity of fullerene and its water-soluble derivatives. To solve the problem, two ways to deal with the toxicity (cytotoxicity mechanism and genotoxicity mechanism) are proposed. In addition, several important factors influencing the toxicity of fullerene and its water-soluble derivatives are introduced, including the light irradiation, preparation method, molecular structure, nanoparticle size and special object. Moreover, it has to be pointed out that long-term exposure of low concentration C6o can cause oxidative damage to tissues of human bodies. Last of all, some important research perspectives in this field have also been summarized and proposed." @default.
- W2359014722 created "2016-06-24" @default.
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- W2359014722 date "2009-01-01" @default.
- W2359014722 modified "2023-09-27" @default.
- W2359014722 title "Review on the research advances in eco-toxicity of fullerene and its water-soluble derivatives" @default.
- W2359014722 hasPublicationYear "2009" @default.
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