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- W2359083049 abstract "Objective To study the difference of efficacy and side effect of aripiprazole and other antipsychotics in the treatment of schizophrenia.Methods 12 comparative studies of aripiprazole and other antipsychotics in the treatment of schizophrenia were analyzed by meta-analysis.Results The significant difference in change of symptoms before and after treatment by aripiprazole was found,d=2.64,95%CI(2.33,2.96),χ2=16.55,P0.05.Comparison between aripiprazole and the controlled antipsychotics at the end of 2nd week and at the end of each trial showed that yco=-0.08,95%CI(-0.20,0.05),χ2=1.15,P0.05,and yco=-0.07,95%CI(-0.19,0.06),χ2=1.00,P0.05 respectively,which revealed that trere was no significant difference between aripiprazole and controlled antipsychotics with respect to the clinical efficacy.The common adverse reactions such as nausea and vomit,insomania,dizziness,astriction and sight obscure were found no significant difference between two groups,the other side effects were lower in aripiprazole group than that in controlled antipsychotics group(χ2=8.88~19.89,P0.01).Conclusion Aripiprazole has a similar clinical effecacy compared with controlled antipsychotics,but not in therapeutic effects." @default.
- W2359083049 created "2016-06-24" @default.
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- W2359083049 date "2008-01-01" @default.
- W2359083049 modified "2023-09-23" @default.
- W2359083049 title "Meta-analysis of comparative study on aripiprazole in the treatment of schizophrenia" @default.
- W2359083049 hasPublicationYear "2008" @default.
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