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- W2359092519 abstract "OBJECTIVE: To establish the method for the content determining of Indomethacin colon-targeting capsule in artificial colon juice. METHODS: RP-HPLC method was adopted. The determination was performed on Hypersil ODS2 C18 column with mobile phase consisted of acetonitrile-0.1 mol·L-1 glacial acetic acid(60 ∶ 40) at flow rate of 1 mL·min-1. The detection wavelength was set at 228 nm and the column temperature was 25 ℃. The injection volume was 20 μL. RESULTS:The linear range of indomethacin was 2.0～50.0 μg·mL-1(r=0.999 9). The recovery rates of it at low, medium and high concentrations were 100.37%,99.87%,100.00% with RSD of 0.29%, 0.31%, 0.74%, respectively. CONCLUTION: The method is accurate, reliable and precision for the content determination of indomethacin in artificial colon juice." @default.
- W2359092519 created "2016-06-24" @default.
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- W2359092519 date "2011-01-01" @default.
- W2359092519 modified "2023-09-26" @default.
- W2359092519 title "Content Determination of Indomethacin in Artificial Colon Juice by RP-HPLC" @default.
- W2359092519 hasPublicationYear "2011" @default.
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