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- W2359093038 abstract "A simple and sensitive spectrophotometric method is described for the determination of cefotaxime.The method is based on the degradation of cefotaxime which was carried out in 0.3 mol/L NaOH solution at 100 ℃,and can be oxidized by Fe(Ⅲ) in acidic solution.Fe(Ⅱ) can form a complex with o-phenanthroline hydrate,of which the maximum absorption wavelength is at 508 nm,e=1.1×104 L(mol·cm).The Beer′s law is obeyed in the range of 0.4~80 μg/mL for cefotaxime.The linear regression equation is A=-0.00204+0.01989C(μg/mL),with a linear correlation coefficient of 0.9998.The detection limit is 0.18 μg/mL. RSD is 1.2%(5.0 μg/mL,n=11),and average recovery is 99%.The reaction mechanism is studied intensively.This proposed method has been successfully applied to the determination of cefotaxime with satisfactory results." @default.
- W2359093038 created "2016-06-24" @default.
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- W2359093038 date "2007-01-01" @default.
- W2359093038 modified "2023-09-23" @default.
- W2359093038 title "Spectrophotometric indirect determination of cefotaxime by o-phenanthroline hydrate-Iron(II)" @default.
- W2359093038 hasPublicationYear "2007" @default.
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