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- W2359095698 abstract "Objective To evaluate the effects of FQ-PCR and Western blotting (WB) in detection of placental Treponema pallidum DNA for diagnosis of congenital syphilis. Methods Thirty-four placental specimens from pregnant women with syphilis and forty specimens from health pregnant women were evaluated by using double blind methods: (1)FQ-PCR and WB for placental Treponema pallidum DNA;(2)Traditional comprehensive approach for the diagnosis of congenital syphilis. The results were compared. Results Positive FQ-PCR (9 congenital syphilis) was observed in 11 out of the 34 placental specimens from syphilitic women, 10 positive serum IgM was detected by Western blot (9 congenital syphilis). No positive results were observed in the 40 infants from health mothers. Conclusion The diagnostic value of FQ-PCR and Western blot in detection of placental Treponema pallidum DNA and serum IgM is superior to any one of the conventional methods." @default.
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- W2359095698 date "2006-01-01" @default.
- W2359095698 modified "2023-09-24" @default.
- W2359095698 title "The value of FQ-PCR and Western blot in early diagnosis of congenital syphilis" @default.
- W2359095698 hasPublicationYear "2006" @default.
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