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- W2359097162 abstract "Objective:To explore the relationship of endothelial nitric oxide synthase(eNOS) G894T with traditional Chinese medical(TCM) syndrome patterns in essential hypertension(EH) patients.Methods:Polymerase chain reaction-restriction fragment length polymorphism(PCRRFLP) was used to detect the mutation frequency of eNOS C894T in 168 EH patients and in 42 volunteers with normal blood pressure.The genotype frequency and allele frequency of eNOS G894T in the two groups were detected,and the relationship of TCM syndrome patterns with eNOS G894T gene polymorphism was investigated.Results:The genotype frequency of eNOS G894T in the two groups was subjecting to Hardy-Weinberg balance,the difference being very significant(P0.01).The incidence of eNOS G894T genotype TT homozygote was higher in EH patients with hyperactivity of liver fire than that in EH patients with deficiency of yin and yang(P0.05).The difference was insignificant between the other TCM syndrome patterns.Conclusion:EH patients with different TCM syndrome patterns present some features of molecular genetics,which is worth of further research." @default.
- W2359097162 created "2016-06-24" @default.
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- W2359097162 date "2009-01-01" @default.
- W2359097162 modified "2023-09-26" @default.
- W2359097162 title "Relationship Between Endothelial Nitric Oxide Synthase G894T and Traditional Chinese Medical Syndrome Patterns in Essential Hypertension Patients" @default.
- W2359097162 hasPublicationYear "2009" @default.
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