Matches in SemOpenAlex for { <https://semopenalex.org/work/W2359124019> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2359124019 abstract "Objective: To compare functional α 1 adrenoceptor and its subtypes in isolated aortae among 5 7 day , 5 6 month and 18 month old rats. Methods: Vasoconstrictor response was measured. Results: The NE induced maximal contraction was significantly lower in 5 7 day old rats than that in the 5 6 month and 18 month old rats. The pA 2 value for WB4101 (an α 1A and α 1D selective antagonist) was not changed among 5 7 day , 5 6 month and 18 month old rats. The pA 2 value for BMY7378 (α 1D selective antagonist) and Sertindole (α 1A selective antagonist) had no difference between 5 7 day and 5 6 month old rats. The pA 2 value for BMY7317 was decreased, and that for Sertindole was increased in the 18 month old rats. The inhibitory effect of chlorethyclonidine (an irreversible antagonist for α 1B and α 1D AR subtypes) on NE induced contraction in 18 month old rats was weaker than that in 5 6 month old rats. Conclusion: During the development, α 1D subtype of α 1 adrenoceptor was mainly seen in both infancy and adult rat aortae. In aged rat aortae, the ratio of α 1A AR subtype of functional α 1 adrenoceptor was markedly increased." @default.
- W2359124019 created "2016-06-24" @default.
- W2359124019 creator A5071702722 @default.
- W2359124019 date "1999-01-01" @default.
- W2359124019 modified "2023-09-25" @default.
- W2359124019 title "Comparison of functional α_1 adrenoceptor subtypes in aortae of rats with different ages" @default.
- W2359124019 hasPublicationYear "1999" @default.
- W2359124019 type Work @default.
- W2359124019 sameAs 2359124019 @default.
- W2359124019 citedByCount "0" @default.
- W2359124019 crossrefType "journal-article" @default.
- W2359124019 hasAuthorship W2359124019A5071702722 @default.
- W2359124019 hasConcept C126322002 @default.
- W2359124019 hasConcept C134018914 @default.
- W2359124019 hasConcept C163415756 @default.
- W2359124019 hasConcept C170493617 @default.
- W2359124019 hasConcept C2776885963 @default.
- W2359124019 hasConcept C2780777758 @default.
- W2359124019 hasConcept C2780948584 @default.
- W2359124019 hasConcept C513476851 @default.
- W2359124019 hasConcept C71924100 @default.
- W2359124019 hasConceptScore W2359124019C126322002 @default.
- W2359124019 hasConceptScore W2359124019C134018914 @default.
- W2359124019 hasConceptScore W2359124019C163415756 @default.
- W2359124019 hasConceptScore W2359124019C170493617 @default.
- W2359124019 hasConceptScore W2359124019C2776885963 @default.
- W2359124019 hasConceptScore W2359124019C2780777758 @default.
- W2359124019 hasConceptScore W2359124019C2780948584 @default.
- W2359124019 hasConceptScore W2359124019C513476851 @default.
- W2359124019 hasConceptScore W2359124019C71924100 @default.
- W2359124019 hasLocation W23591240191 @default.
- W2359124019 hasOpenAccess W2359124019 @default.
- W2359124019 hasPrimaryLocation W23591240191 @default.
- W2359124019 hasRelatedWork W1993163366 @default.
- W2359124019 hasRelatedWork W2034493393 @default.
- W2359124019 hasRelatedWork W2064810018 @default.
- W2359124019 hasRelatedWork W2071051266 @default.
- W2359124019 hasRelatedWork W2080724159 @default.
- W2359124019 hasRelatedWork W2083641830 @default.
- W2359124019 hasRelatedWork W2119824206 @default.
- W2359124019 hasRelatedWork W2119972299 @default.
- W2359124019 hasRelatedWork W2134452817 @default.
- W2359124019 hasRelatedWork W2154033030 @default.
- W2359124019 hasRelatedWork W2321993038 @default.
- W2359124019 hasRelatedWork W2351149912 @default.
- W2359124019 hasRelatedWork W2351236797 @default.
- W2359124019 hasRelatedWork W2357869067 @default.
- W2359124019 hasRelatedWork W2361239362 @default.
- W2359124019 hasRelatedWork W2362932881 @default.
- W2359124019 hasRelatedWork W2375799756 @default.
- W2359124019 hasRelatedWork W2377078550 @default.
- W2359124019 hasRelatedWork W2407254199 @default.
- W2359124019 hasRelatedWork W2419257812 @default.
- W2359124019 isParatext "false" @default.
- W2359124019 isRetracted "false" @default.
- W2359124019 magId "2359124019" @default.
- W2359124019 workType "article" @default.