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- W2359132023 abstract "OBJECTIVE To compare the distribution and drug resistance of Pseudomonas aeruginosa in ICU and common wards so as to guide the clinical rational use of antimicrobial drugs.METHODS The P.aeruginosa isolates were detected by VITEK-32 and VITEK-2 compact system,and antimicrobial susceptibility was tested by K-B method.The significance of the resistant rate was analyzed by χ2.RESULTS A total of 341 strains of P.aeruginosa were isolated,which were mainly from sputum(62.5%);most isolates distributed in ICU,accounting for 51.3%;the infection rate was the highest in autumn(34.0%),there was little difference in the monthly distribution of P.aeruginosa between the ICU and the common wards;the resistance rate of the isolates from ICU was 27.4%,the common wards 5.4%,the difference was statistically significant(P0.05);the resistant rates of P.aeruginosa isolates from ICU to amikacin,cefepime,gentamicin,levofloxacin,ceftazidime,tobramycin,and piperacillin/tazobactam were higher than from the common wards,the difference was statistically significant(P0.005);of the P.aeruginosa isolates from ICU,multidrug-resistant(MDR) and pan-drug resistant(PDR) strains accounted for 53.2% and 18.8%,respectively;of the isolates from the common wards,MDR and PDR strains accounted for 14.5% and 3.6%,the difference was statistically significant(P0.05).CONCLUSION P.aeruginosa isolates are mainly isolated from sputum,it is necessary to strengthen the disinfections,which is conducive to the reduction of P.aeruginosa infections;the drug resistance of P.aeruginosa isolates from ICU is significantly higher than from the common wards;the isolation rates of MDR and PDR strains are so high,MDR strains from ICU is more than 50.0%,and the drug resistance is serious." @default.
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- W2359132023 date "2012-01-01" @default.
- W2359132023 modified "2023-09-24" @default.
- W2359132023 title "Distribution and drug resistance of Pseudomonas aeruginosa infections in ICU and common wards" @default.
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