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- W2359162230 abstract "To explore the medicinal value of silkworm Cordyceps militaris,the protective effects of mycelial water extract from silkworm Cordyceps militaris to CCl4-induced hepatic and immunologic function impaired mice were investigated.Male ICR mice were randomly assigned into four groups,namely normal control group,model group,low-and high-dosage groups [0.2 and 0.4 g/(kg·d)] of mycelial water extract from silkworm Cordyceps militaris.Except the normal control group,all mice of the rest groups were induced with CCl4 through intraperitoneal injection at a dosage of 30 mg/kg.Determination of AST,ALT,IL-2,TNF-α and IFN-γ contents in mouse serum indicated that the mycelial water extract from silkworm Cordyceps militaris could extremely significantly increase the IL-2 and IFN-γ levels(P0.01) and extremely significantly reduce activity of AST and ALT and content of TNF-α(P0.01) in mouse serum.These results indicated that mycelial water extract from silkworm Cordyceps militaris had evident protective effect on CCl4-induced hepatic mice.Besides,it reduced TNF-α level and regulat-ed the immunologic function of CCl4 model mice through promoting secretion of IL-2 and IFN-γ,displaying its role in anti liver fibrosis mechanism." @default.
- W2359162230 created "2016-06-24" @default.
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- W2359162230 date "2011-01-01" @default.
- W2359162230 modified "2023-09-25" @default.
- W2359162230 title "Protective Effects of Mycelial Water Extract from Silkworm Cordy-ceps militaris to CCl_4-induced Hepatic and Immunologic Function Impaired Mice" @default.
- W2359162230 hasPublicationYear "2011" @default.
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