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- W2359183734 abstract "Objective: To study the role of Hsp70 in pathogensis in CryPtococcus neofOrmans under different tbermal cir-cumstances. Methods: Using the mouse's antibody to Hsp70 of human, pig, dog, etc., we detected 6 clinically isolatedstrains and 1 CZYD2 standard strain of Cryptococcus neoformans by Western blotting. According to the different hybridiza-tional signal, the production of Hsp70 was qualitatively determined. Results: The production of Hsp70 in the yeasts stressedby 42℃×30 min and cultured in 37℃×48 h was higher than that cu1tured in 30℃. Conclusion: The production of Hsp70 ismore in refractory cases, indicating patients infected by the yeasts with stronger heat shock reaction are more difficult to becured. So HSR has effects on pathogenesis in CryPtococcus neoformans I And the antibody of Hsp70 of the yeast may responsecrossing reaction with the Hsp70 of human. It may be a factor in pathogenesis of the yeast." @default.
- W2359183734 created "2016-06-24" @default.
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- W2359183734 date "2002-01-01" @default.
- W2359183734 modified "2023-09-28" @default.
- W2359183734 title "Heat shock reaction in Cryptococcus neoformans: difference and its clinical significance" @default.
- W2359183734 hasPublicationYear "2002" @default.
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